Recognizing misfolded and distorted protein structures by the assumption-based similarity score
نویسندگان
چکیده
منابع مشابه
Recognizing misfolded and distorted protein structures by the assumption-based similarity score.
A new similarity score (sigma-score) is proposed which is able to find the correct protein structure among the very close alternatives and to distinguish between correct and deliberately misfolded structures. This score is based on the general principle 'similar likes similar', and it favors hydrophobic and hydrophilic contacts, and disfavors hydrophobic-to-hydrophilic contacts in proteins. The...
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ژورنال
عنوان ژورنال: Protein Engineering, Design and Selection
سال: 1999
ISSN: 1741-0134,1741-0126
DOI: 10.1093/protein/12.1.31